Article
Extensive genomic and transcriptional diversity identified through massively parallel DNA and RNA sequencing of eighteen Korean individuals.
Nature genetics - 3 Jul 2011
Ju Young Seok, Kim Jong-Il, Kim Sheehyun, Hong Dongwan, Park Hansoo, Shin Jong-Yeon, Lee Seungbok, Lee Won-Chul, Kim Sujung, Yu Saet-Byeol, Park Sung-Soo, Seo Seung-Hyun, Yun Ji-Young, Kim Hyun-Jin, Lee Dong-Sung, Yavartanoo Maryam, Kang Hyunseok Peter, Gokcumen Omer, Govindaraju Diddahally R, Jung Jung Hee, Chong Hyonyong, Yang Kap-Seok, Kim Hyungtae, Lee Charles, Seo Jeong-Sun
Abstract excerpt
Massively parallel sequencing technologies have identified a broad spectrum of human genome diversity. Here we deep sequenced and correlated 18 genomes and 17 transcriptomes of unrelated Korean individuals. This has allowed us to construct a genome-wide map of common and rare variants and also identify variants formed during DNA-RNA transcription. We identified 9.56 million genomic variants, 23.2% of which appear...
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