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Article

Resolving the variable genome and epigenome in human disease.

Journal of internal medicine - 1 Apr 2012

Knight J C

Abstract excerpt

The individual human genome and epigenome are being defined at unprecedented resolution by current advances in sequencing technologies with important implications for human disease. This review uses examples relevant to clinical practice to illustrate the functional consequences of genetic and epigenetic variation. The insights gained from genome-wide association studies are described together with current...

Topics

Alleles
Disease
Epigenomics
Genetic Linkage
Genetic Predisposition to Disease
Genetic Variation
Genome, Human
Genome-Wide Association Study
Humans

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22443201
DOI: 10.1111/j.1365-2796.2011.02508.x
PMCID: PMC4442130

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