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Article

Evaluation of chemoradiotherapy with carbon ions and the influence of p53 mutational status in the colorectal carcinoma cell line HCT 116.

Tumori - 1 Jan 2000

Adeberg Sebastian, Baris Daniela, Habermehl Daniel, Rieken Stefan, Brons Stefan, Weber Klaus-Josef, Roth Wilfried, Debus Jürgen, Combs Stephanie E

Abstract excerpt

AIMS AND BACKGROUND: Heavy ion therapy has shown promising results in the treatment of recurrent colorectal carcinoma. The present study evaluates the effect of five different cytostatic agents in combination with radiotherapy with carbon (C12) ions and photons in two isogenic colorectal cancer cell lines differing in p53 status. METHODS AND STUDY DESIGN: Clonogenic survival analyses were performed using the...

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Identifiers

PMID: 25688502
DOI: 10.1700/1778.19278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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