Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Carbon ion radiotherapy of human lung cancer attenuates HIF‐1 signaling and acts with considerably enhanced therapeutic efficiency

17 Dec 2013

Abstract excerpt

Carbon ion irradiation is an emerging therapeutic option for various tumor entities. Radiation resistance of solid tumors toward photon irradiation is caused by attenuation of DNA damage in less oxygenated tumor areas and by increased hypoxia‐inducible factor (HIF)‐1 signaling. Carbon ion irradiation acts independently of oxygen;however, the role of HIF‐1 is unclear. We analyzed the effect of HIF‐1 signaling...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced Radiotherapy Techniques
Share to Cancer, Hypoxia, and Metabolism
Share to Radiation Therapy and Dosimetry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24347608
DOI: 10.1096/fj.13-242230

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Carbon ion radiotherapy of human lung cancer attenuates HIF‐1 signaling and acts with considerably enhanced therapeutic efficiencyPMID 24347608Read ↗

Carbon ion irradiation suppresses angiogenic response in human lung adenocarcinoma cells mediated by LINC00167/miR-663a/TGF-β1 axisSemantic proximity Read ↗

Carbon Ion Radiotherapy: A Review of Clinical Experiences and Preclinical Research, with an Emphasis on DNA Damage/RepairSemantic proximity Read ↗

Hypoxia Modulates Radiosensitivity and Response to Different Radiation Qualities in A549 Non-Small Cell Lung Cancer (NSCLC) CellsSemantic proximity Read ↗

Proton Irradiation Suppresses Angiogenic Genes and Impairs Cell Invasion and Tumor GrowthSemantic proximity Read ↗

Radio-sensitization of mutated KRAS G12C non-small cell lung cancer with KRAS G12C tyrosine kinase inhibitor and Carbon ions irradiationSemantic proximity Read ↗

Impact of hypoxia on the double-strand break repair after photon and carbon ion irradiation of radioresistant HNSCC cells.Semantic proximity Read ↗

Irradiation With Carbon Ion Beams Induces Apoptosis, Autophagy, and Cellular Senescence in a Human Glioma-Derived Cell LineSemantic proximity Read ↗

Radiotherapy triggers pro-angiogenic signaling in human lungSemantic proximity Read ↗

Difference in Acquired Radioresistance Induction Between Repeated Photon and Particle IrradiationSemantic proximity Read ↗

The EGFR mutation status affects the relative biological effectiveness of carbon-ion beams in non-small cell lung carcinoma cells.Semantic proximity Read ↗

Proteomics of the radioresistant phenotype in H1299 cells: SLC2A1 as a radiosensitivity markerSemantic proximity Read ↗

Primary and Secondary Bystander Effects of Proton Microbeam Irradiation on Human Lung Cancer Cells under Hypoxic ConditionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.