Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhanced sensitivity of human colon tumor cell lines in vitro in response to thermochemoimmunotherapy.

Cancer research - 1 Oct 1992

Klostergaard J, Leroux E, Siddik Z H, Khodadadian M, Tomasovic S P

Abstract excerpt

We have investigated the cytotoxic responses in vitro of three human colon tumor cell lines with epithelial-like morphology, DLD-1, HCT-15, and HT-29, to thermochemoimmunotherapy with hyperthermia (42 degrees C for 2 h), carboplatin, and recombinant human tumor necrosis factor (TNF). Dose ranges of carboplatin and recombinant human TNF were administered essentially simultaneously and were followed 1 h later by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Antineoplastic Combined Chemotherapy Protocols

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Colonic Neoplasms

Share to TNF gene

Share to Phenotype

Share to Sensitivity and Specificity

Share to Tumor Cells, Cultured

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 1394131

Genes

TNF
DLD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhanced sensitivity of human colon tumor cell lines in vitro in response to thermochemoimmunotherapy.PMID 1394131Read ↗

Step-down heating enhances the cytotoxicity of human tumour necrosis factor on murine and human tumour cell lines in vitro.Semantic proximity Read ↗

Cellular Response to Chemoradiotherapy, Radiotherapy and Chemotherapy in Two Colorectal Cancer Cell LinesSemantic proximity Read ↗

Cytotoxic drugs up-regulate epidermal growth factor receptor (EGFR) expression in colon cancer cells and enhance their susceptibility to EGFR-targeted antibody-dependent cell-mediated-cytotoxicity (ADCC).Semantic proximity Read ↗

Wild-type p53 gene transfer into mutated p53 HT29 cells improves sensitivity to photodynamic therapy via induction of apoptosis.Semantic proximity Read ↗

Low-temperature plasma-induced antiproliferative effects on multi-cellular tumor spheroidsSemantic proximity Read ↗

CPT-11 in human colon-cancer cell lines and xenografts: Characterization of cellular sensitivity determinantsSemantic proximity Read ↗

In Vitro Induction of PDT Resistance in HT29, HT1376 and SK-N-MC Cells by Various Photosensitizers¶Semantic proximity Read ↗

Activation of NF-kappaB determines the sensitivity of human colon cancer cells to TNFalpha-induced apoptosis.Semantic proximity Read ↗

Differential photosensitivity in wild-type and mutant p53 human colon carcinoma cell lines.Semantic proximity Read ↗

p53 dependence and apoptosis in response to FP treatment with p53-transfected colon cancer cell lines by use of thin layer collagen gel.Semantic proximity Read ↗

A study of the growth and differentiation of the human adenocarcinoma of the colon cell line HT-29Semantic proximity Read ↗

Cellular basis for differential sensitivity to cisplatin in human germ cell tumour and colon carcinoma cell linesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.