Article
Radiation-stimulated ERK1/2 and JNK1/2 signaling can promote cell cycle progression in human colon cancer cells.
Cell cycle (Georgetown, Tex.) - 1 Mar 2005
Carón Rubén W, Yacoub Adly, Mitchell Clint, Zhu Xiaoyu, Hong Young, Sasazuki Takehiko, Shirasawa Senji, Hagan Michael P, Grant Steven, Dent Paul
Abstract excerpt
The abilities of mutated active K-RAS and H-RAS proteins, in an isogenic human carcinoma cell system, to modulate the activity of signaling pathways and cell cycle progression following exposure to ionizing radiation is largely unknown. Loss of K-RAS D13 expression in parental HCT116 colorectal c...
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