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Article

H-RAS V12-induced radioresistance in HCT116 colon carcinoma cells is heregulin dependent.

Molecular cancer therapeutics - 1 Feb 2005

Carón Rubén W, Yacoub Adly, Zhu Xiaoyu, Mitchell Clint, Han Song Iy, Sasazuki Takehiko, Shirasawa Senji, Hagan Michael P, Grant Steven, Dent Paul

Abstract excerpt

The abilities of mutated active K-RAS and H-RAS proteins, in an isogenic human carcinoma cell system, to modulate the activity of signaling pathways following exposure to ionizing radiation is unknown. Loss of K-RAS D13 expression in HCT116 colorectal carcinoma cells blunted basal extracellular s...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15713896

Genes

ERBB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15713896-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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