Article
Genome-wide pathway analysis of breast cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2014
Lee Young Ho, Kim Jae-Hoon, Song Gwan Gyu
Abstract excerpt
The aim of this study was to identify candidate single-nucleotide polymorphisms (SNPs) that might affect susceptibility to breast cancer and then elucidate their potential mechanisms and generate SNP-to-gene-to-pathway hypotheses. A genome-wide association study (GWAS) dataset of breast cancer that included 453,852 SNPs from 1,145 breast cancer patients and 1,142 control subjects of European descent was used in...
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