Article
A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1.
Nature genetics - 30 Oct 2011
Shi Yongyong, Hu Zhibin, Wu Chen, Dai Juncheng, Li Huizhang, Dong Jing, Wang Meilin, Miao Xiaoping, Zhou Yifeng, Lu Feng, Zhang Hanze, Hu Lingmin, Jiang Yue, Li Zhiqiang, Chu Minjie, Ma Hongxia, Chen Jiaping, Jin Guangfu, Tan Wen, Wu Tangchun, Zhang Zhengdong, Lin Dongxin, Shen Hongbing
Abstract excerpt
Gastric cancer, including the cardia and non-cardia types, is the second leading cause of cancer-related deaths worldwide. To identify genetic risk variants for non-cardia gastric cancer, we performed a genome-wide association study in 3,279 individuals (1,006 with non-cardia gastric cancer and 2,273 controls) of Chinese descent. We replicated significant associations in an additional 6,897 subjects (3,288 with...
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