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Article

14q32-encoded microRNAs mediate an oligometastatic phenotype.

Oncotarget - 28 Feb 2015

Uppal Abhineet, Wightman Sean C, Mallon Stephen, Oshima Go, Pitroda Sean P, Zhang Qingbei, Huang Xiaona, Darga Thomas E, Huang Lei, Andrade Jorge, Liu Huiping, Ferguson Mark K, Greene Geoffrey L, Posner Mitchell C, Hellman Samuel, Khodarev Nikolai N, Weichselbaum Ralph R

Abstract excerpt

Oligometastasis is a clinically distinct subset of metastasis characterized by a limited number of metastases potentially curable with localized therapies. We analyzed pathways targeted by microRNAs over-expressed in clinical oligometastasis samples and identified suppression of cellular adhesion, invasion, and motility pathways in association with the oligometastatic phenotype. We identified miR-127-5p,...

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Identifiers

PMID: 25686838
DOI: 10.18632/oncotarget.2920
PMCID: PMC4414135

Genes

ROCK2
TGFBR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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