Article
A clinicogenetic model to predict lymph node invasion by use of genome-based biomarkers from exome arrays in prostate cancer patients.
Korean journal of urology - 1 Feb 2015
Oh Jong Jin, Park Seunghyun, Lee Sang Eun, Hong Sung Kyu, Lee Sangchul, Lee Hak Min, Lee Jeung Keun, Ho Jin-Nyoung, Yoon Sungroh, Byun Seok-Soo
Abstract excerpt
PURPOSE: Genetic variations among prostate cancer (PCa) patients who underwent radical prostatectomy (RP) and pelvic lymph node dissection were evaluated to predict lymph node invasion (LNI). Exome arrays were used to develop a clinicogenetic model that combined clinical data related to PCa and individual genetic variations. MATERIALS AND METHODS: We genotyped 242,186 single-nucleotide polymorphisms (SNPs) by...
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