Article
Predictive performance of prostate cancer risk in Chinese men using 33 reported prostate cancer risk-associated SNPs.
The Prostate - 1 Apr 2012
Zheng Jie, Liu Fang, Lin Xiaoling, Wang Xiang, Ding Qiang, Jiang Haowen, Chen Hongyan, Lu Daru, Jin Guangfu, Hsing Ann W, Shao Qiang, Qi Jun, Ye Yu, Wang Zhong, Gao Xin, Wang Guozeng, Chu Lisa W, Ouyang Jun, Huang Yichen, Chen Yanbo, Gao Yutang, Shi Rong, Wu Qijun, Wang Meilin, Zhang Zhengdong, Hu Yanlin, Sun Jielin, Zheng S Lilly, Gao Xu, Xu Chuanliang, Mo Zengnan, Sun Yinghao, Xu Jianfeng
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) have identified more than 30 single nucleotide polymorphisms (SNPs) that were reproducibly associated with prostate cancer (PCa) risk in populations of European descent. In aggregate, these variants have shown potential to predict risk for PCa in European men. However, their utility for PCa risk prediction in Chinese men is unknown. METHODS: We selected 33 PCa...
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