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Article

Interleukin-4 affects the mature phenotype and function of rat bone marrow-derived dendritic cells.

Molecular medicine reports - 1 Jul 2015

Wang Shizhong, Sun Xiao, Zhou Haijun, Zhu Zhichao, Zhao Wenjie, Zhu Chunfu

Abstract excerpt

Granulocyte macrophage‑colony stimulating factor (GM‑CSF), and GM‑CSF plus interleukin‑4 (GM‑CSF + IL‑4) are two commonly‑used cytokine therapies for the generation of bone marrow‑derived dendritic cells (DCs). However, the mechanisms underlying IL‑4 involvement in DC generation and maturation remain unclear. In order to investigate the effect of IL‑4 on DC generation, DCs from rat bone marrow progenitors were...

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PMID: 25683957
DOI: 10.3892/mmr.2015.3349

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STAT6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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