Article
Rat bone marrow-derived dendritic cells generated with GM-CSF/IL-4 or FLT3L exhibit distinct phenotypical and functional characteristics.
Journal of leukocyte biology - 1 Mar 2016
N'diaye Marie, Warnecke Andreas, Flytzani Sevasti, Abdelmagid Nada, Ruhrmann Sabrina, Olsson Tomas, Jagodic Maja, Harris Robert A, Guerreiro-Cacais Andre Ortlieb
Abstract excerpt
Dendritic cells are professional APCs that play a central role in the initiation of immune responses. The limited ex vivo availability of dendritic cells inspires the widespread use of bone marrow-derived dendritic cells as an alternative in research. However, the functional characteristics of bone marrow-derived dendritic cells are incompletely understood. Therefore, we compared functional and phenotypic...
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