Phenotypic and functional patterns of murine bone marrow-derived dendritic cells influenced by in vitro differentiation conditions.

doi:10.1371/journal.pone.0356806

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Article

Phenotypic and functional patterns of murine bone marrow-derived dendritic cells influenced by in vitro differentiation conditions.

PloS one - 1 Jan 2026

Ionescu Irina Elena, Tucureanu Catalin, Chelmus Raluca Elena, Tofan Vlad Constantin, Ionita Fabiola Margareta, Onu Adrian, Neagu Monica, Stavaru Crina, Caras Iuliana

Abstract excerpt

The selection of an appropriate differentiation protocol for murine bone marrow-derived dendritic cells (BM-DCs) still presents a challenge due to the inherent plasticity of dendritic cells (DCs) and the high diversity of generation methods. As such, it is essential to evaluate in vitro BM-DCs characteristics during initial steps of experimental model development and tailor the protocols according to specific...

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PMID: 42647452
DOI: 10.1371/journal.pone.0356806
PMCID: PMC13513930

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