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Article

Positive Association of D Allele of ACE Gene With High Altitude Pulmonary Edema in Indian Population.

Wilderness & environmental medicine - 1 Jun 2015

Bhagi Shuchi, Srivastava Swati, Tomar Arvind, Bala Singh Shashi, Sarkar Soma

Abstract excerpt

OBJECTIVE: High altitude pulmonary edema (HAPE) is a potentially fatal high altitude illness occurring as a result of hypobaric hypoxia with an unknown underlying genetic mechanism. Recent studies have shown a possible association between HAPE and polymorphisms in genes of the renin-angiotensin-aldosterone system (RAAS), which play a key role in sensitivity of an individual toward HAPE. METHODS: For the present...

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Source

Identifiers

PMID: 25683681
DOI: 10.1016/j.wem.2014.09.010

Genes

ACE
AGT
REN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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