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Article

Correlation between single nucleotide polymorphisms in hypoxia-related genes and susceptibility to acute high-altitude pulmonary edema.

Genetics and molecular research : GMR - 28 Sept 2015

Wu A L, Xiong Y S, Li Z Q, Liu Y G, Quan Q, Wu L J

Abstract excerpt

This study aimed to explore the relationship between genetic changes and high-altitude pulmonary edema (HAPE) susceptibility, and to screen for the key single nucleotide polymorphism (SNP) loci in the HAPE-susceptibility gene, by investigating the SNPs occurring in hypoxia-related genes in HAPE-susceptible and control (non-susceptible) populations. This research was conducted on Han recruits, who travelled to the...

Topics

Acute Disease
Alleles
Altitude
Base Sequence
DNA Mutational Analysis
DNA-Binding Proteins
Gene Frequency
Genetic Loci
Genetic Predisposition to Disease
HSP70 Heat-Shock Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Heterozygote

Homozygote

Humans

Hypoxia

Intracellular Signaling Peptides and Proteins

Molecular Sequence Data

NF-kappa B

Nitric Oxide Synthase

Source

Identifiers

PMID: 26436397
DOI: 10.4238/2015.September.28.8

Genes

ACE
EGLN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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