Article
Gene polymorphisms and high-altitude pulmonary edema susceptibility: a 2011 update.
Respiration; international review of thoracic diseases - 1 Jan 2012
Luo Yongjun, Zou Yanlong, Gao Yuqi
Abstract excerpt
High-altitude pulmonary edema (HAPE) is a severe disease caused by high-altitude hypoxia. Since some individuals are more susceptible to high altitude than others, the incidence is variable and cannot be predicted. Furthermore, multiple genes can contribute to the occurrence of HAPE, making it even more difficult to predict. The genes associated with HAPE include those in the renin-angiotensin-aldosterone system...
Topics
- Altitude Sickness
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
- Hypertension, Pulmonary
- Hypoxia
- Polymorphism, Genetic