Article
Angiotensin II receptor 1 gene variants are associated with high-altitude pulmonary edema risk.
Oncotarget - 22 Nov 2016
Jin Tianbo, Ren Yongchao, Zhu Xikai, Li Xun, Ouyang Yongri, He Xue, Zhang Zhiying, Zhang Yuan, Kang Longli, Yuan Dongya
Abstract excerpt
Previous studies demonstrated that Angiotensin II Receptor 1 (AGTR1) may play an important role in the development of high-altitude pulmonary edema. We envisaged a role for AGTR1 gene variants in the pathogenesis of HAPE and investigated their potential associations with HAPE in a Han Chinese population. We genotyped seven AGTR1 polymorphisms in 267 patients with diagnosed HAPE and 304 controls and evaluated...
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