Article
The association of angiotensin-converting enzyme gene insertion/deletion polymorphisms with adaptation to high altitude: A meta-analysis.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Jan 2000
Wang Yuxiao, Lu Hongxiang, Chen Yu, Luo Yongjun
Abstract excerpt
BACKGROUND: Fluid retention is linked to the physiology and pathophysiology of humans at high altitude (HA). The angiotensin-converting enzyme (ACE) gene plays a role in the regulation of plasma volume and vascular tone. MATERIALS AND METHODS: In this meta-analysis, eligible studies published before 1 September 2015 that focused on the association between the ACE insertion/deletion (I/D) polymorphism and HA...
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