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Article

Association of polymorphisms in angiotensin and aldosterone synthase genes of the renin-angiotensin-aldosterone system with high-altitude pulmonary edema.

Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Mar 2012

Srivastava Swati, Bhagi Shuchi, Kumari Babita, Chandra Khem, Sarkar Soma, Ashraf Mohammad Z

Abstract excerpt

Studies on different populations have suggested variability in individual susceptibility to altitude sickness depending on genetic makeup. The renin-angiotensin-aldosterone system (RAAS) pathway plays a key role in regulation of vascular tone and circulatory homeostasis. The present study was undertaken to investigate the possible association of the RAAS in the development of high-altitude pulmonary edema (HAPE)...

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Topics

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Share to Altitude Sickness
Share to Angiotensins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP11B2

Share to Epistasis, Genetic

Share to Genetic Association Studies

Share to Hypertension, Pulmonary

Share to Receptor, Angiotensin, Type 1

Share to Renin-Angiotensin System

Source

Identifiers

PMID: 22156739
DOI: 10.1177/1470320311430990

Genes

AGT
AGTR1
ACE
REN

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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