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Article

Polymorphisms of renin--angiotensin system genes as a risk factor for high-altitude pulmonary oedema.

Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Jun 2011

Stobdan Tsering, Ali Zahara, Khan Amjad Pervez, Nejatizadeh Azim, Ram Rekhbala, Thinlas Tashi, Mohammad Ghulam, Norboo Tsering, Himashree Gidugu, Qadar Pasha Ma

Abstract excerpt

The genes of the renin--angiotensin system (RAS) play an important role in the regulation of pulmonary vascular tone. Although studies on individual genes polymorphisms have reported association with high-altitude pulmonary oedema (HAPE), studies on multiple genes or epistasis are lacking. We therefore investigated the association of the RAS polymorphisms with HAPE. In a case-control design, we screened 163...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21393362
DOI: 10.1177/1470320310387177

Genes

AGT
ACE
AGTR1
AGTR2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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