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Interaction of white matter hyperintensities (WMHs) and apolipoprotein E (APOE) genotypes on cognition in patients with amnestic mild cognitive impairment (aMCI).

Archives of gerontology and geriatrics - 1 Jan 2000

Yoon Bora, Shim Yong S, Cheong Hae-Kwan, Kim Yong-Duk, Lee Kee Ook, Hong Yun-Jeong, Oh Yoon-Sang, Na Hae Ri, Kim Beoung-Chae, Choi Seong Hye, Yang Dong-Won

Abstract excerpt

The clinical implications of WMHs in aMCI are inconclusive. Moreover, clinical interactions between APOE genotypes and WMHs remain unclear. This study was conducted to investigate the relationship between WMHs and cognitive functions and how this relationship interacted with APOE genotype in people with aMCI. This study included a total of 1472 patients with aMCI from the Clinical Research Center for Dementia of...

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Identifiers

PMID: 23688406
DOI: 10.1016/j.archger.2013.04.008

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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