Article
Rationale for targeting fibroblast growth factor receptor signaling in breast cancer.
Breast cancer research and treatment - 1 Feb 2015
André Fabrice, Cortés Javier
Abstract excerpt
Fibroblast growth factor receptor (FGFR) signaling is involved in multiple biological processes, including cell proliferation, survival, differentiation, migration, and apoptosis during embryonic development and adult tissue homeostasis. Given its role in the activation of critical signaling pathways, aberrant FGFR signaling has been implicated in multiple cancer types. A comprehensive search of PubMed and...
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