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Article

Fibroblast Growth Factor Receptor 2 Signaling in Breast Cancer.

International journal of biological sciences - 1 Jan 2017

Lei Haipeng, Deng Chu-Xia

Abstract excerpt

Fibroblast growth factor receptor 2 (FGFR2) is a membrane-spanning tyrosine kinase that mediates signaling for FGFs. Recent studies detected various point mutations of FGFR2 in multiple types of cancers, including breast cancer, lung cancer, gastric cancer, uterine cancer and ovarian cancer, yet the casual relationship between these mutations and tumorigenesis is unclear. Here we will discuss possible...

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Topics

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Share to Breast Neoplasms
Share to Cell Transformation, Neoplastic
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to FGFR2 gene

Share to Mutation

Share to Polymorphism, Genetic

Share to Receptor, Fibroblast Growth Factor, Type 2

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 29104507
DOI: 10.7150/ijbs.20792
PMCID: PMC5666331

Genes

FGFR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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