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Article

Challenges and opportunities in the targeting of fibroblast growth factor receptors in breast cancer.

Breast cancer research : BCR - 19 Jun 2012

Jain Vikram K, Turner Nicholas C

Abstract excerpt

Activation of the fibroblast growth factor receptor pathway is a common event in many cancer types. Here we review the role of fibroblast growth factor receptor signalling in breast cancer, from SNPs in FGFR2 that influence breast cancer risk and SNPs in FGFR4 that associate with breast cancer prognosis, and potential therapeutic targets such as receptor amplification and aberrant autocrine and paracrine ligand...

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Source

Open in PubMed Open full text

Identifiers

PMID: 22731805
DOI: 10.1186/bcr3139
PMCID: PMC3446326

Genes

FGFR2
FGFR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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