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Article

Murine gammaherpesvirus (MHV-68) transforms cultured cells in vitro.

Intervirology - 1 Jan 2015

Mrázová Veronika, Betáková Tatiana, Kúdelová Marcela, Šupolíková Miroslava, Lachová Veronika, Lapuníková Barbora, Golais František

Abstract excerpt

Human dermal fibroblasts and mouse NIH/3T3 cells acquired the transformed phenotype ('criss-cross' pattern of growth) after infection with ultraviolet-irradiated murine gammaherpesvirus (MuHV-4 strain 68; MHV-68). These cells with changed phenotype could be serially cultured for 5-6 passages (35-40 days), and then they entered into crisis and most of them died. In a small number of cultures, however, foci of...

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Identifiers

PMID: 25677084
DOI: 10.1159/000370071

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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