Article
Transformation of Cells by Photoinactivated Murine Gamma-Herpesvirus 68 during Nonproductive and Quiescent Infection.
Intervirology - 1 Jan 2017
Mrázová Veronika, Kúdelová Marcela, Smolinská Miroslava, Nováková Eva, Šupolíková Miroslava, Vrbová Michaela, Golais František
Abstract excerpt
Infection of human MRC-5 cells and mouse NIH-3T3 cells with a murine gamma-herpesvirus (MuHV-4 strain 68; MHV-68) photoinactivated by visible light in the presence of methylene blue (MB) resulted in nonproductive infection and the appearance of morphologically transformed cells. Two stably transformed cell lines were derived from both of these cell types and were confirmed to contain both viral DNA and antigen....
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