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Article

Oncogenic potential of human herpesvirus-6 DNA.

Oncogene - 1 Sept 1990

Razzaque A

Abstract excerpt

The ability of human herpesvirus-6 (HHV-6, GS strain) DNA to neoplastically transform established NIH3T3 cells was examined. Transfection of NIH3T3 cells with the intact genomic DNA (170 Kb) or the subgenomic clone pZVH14 containing an 8.7 Kb insert followed by focal or G418 selection resulted in the formation of morphologically transformed cells. When injected subcutaneously into nude mice, these cell lines gave...

Topics

Animals
Cell Division
Cell Transformation, Neoplastic
Cell Transformation, Viral
Cells, Cultured
DNA, Viral
Female
Fibrosarcoma
Herpesvirus 6, Human
Humans
Mice
Mice, Nude

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Transfection

Source

Identifiers

PMID: 2170897

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2170897-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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