Oncogenic transformation by cellular DNA isolated from human cytomegalovirus-infected cells.

doi:10.1159/000150264

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Article

Oncogenic transformation by cellular DNA isolated from human cytomegalovirus-infected cells.

Intervirology - 1 Jan 1992

Boldogh I, Huang E S, Baskar J F, Gergely L, Albrecht T

Abstract excerpt

Delayed replication of human cytomegalovirus (CMV) was initiated in human embryonic fibroblasts using partially ultraviolet light-inactivated virus stock. Cellular [high molecular weight (HMW)] DNA extracted from CMV-infected cell cultures demonstrated a substantial increase in transforming activ...

Topics

Animals
Cell Line
Cell Transformation, Neoplastic
Cricetinae
Cytomegalovirus
DNA, Viral
Fibrosarcoma
Humans
Molecular Weight
Phenotype
Transfection
Virus Replication

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