Article
Selection of mutant CHO clones resistant to murine gammaherpesvirus 68 infection.
Virology - 10 Apr 2008
Jarousse Nadine, Coscoy Laurent
Abstract excerpt
Murine gammaherpesvirus 68 (MHV68) is used as a model to study gammaherpesvirus pathogenesis both in tissue culture systems and in vivo. We used a gene-trapping approach to get insight into cellular factors involved in MHV68 infection. By generating a library of gene-trapped CHO cells, we were able to isolate several clones that exhibited various degrees of resistance to MHV68-induced cytopathic effect. Clones...
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