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Article

Amygdala function and 5-HTT gene variants in adolescent anxiety and major depressive disorder.

Biological psychiatry - 15 Feb 2009

Lau Jennifer Y F, Goldman David, Buzas Beata, Fromm Stephen J, Guyer Amanda E, Hodgkinson Colin, Monk Christopher S, Nelson Eric E, Shen Pei-Hong, Pine Daniel S, Ernst Monique

Abstract excerpt

BACKGROUND: Associations between a functional polymorphism in the serotonin transporter gene and amygdala activation have been found in healthy, depressed, and anxious adults. This study explored these gene-brain associations in adolescents by examining predictive effects of serotonin transporter gene variants (S and L(G) allele carriers vs. L(A) allele homozygotes) and their interaction with diagnosis (healthy...

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Source

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Identifiers

PMID: 18950748
DOI: 10.1016/j.biopsych.2008.08.037
PMCID: PMC2791528

Genes

HTT

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Source receipt: pubmed, retrieved 7 Sept 2026.

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