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Article

African glucose-6-phosphate dehydrogenase alleles associated with protection from severe malaria in heterozygous females in Tanzania.

PLoS genetics - 1 Feb 2015

Manjurano Alphaxard, Sepulveda Nuno, Nadjm Behzad, Mtove George, Wangai Hannah, Maxwell Caroline, Olomi Raimos, Reyburn Hugh, Riley Eleanor M, Drakeley Christopher J, Clark Taane G

Abstract excerpt

X-linked Glucose-6-phosphate dehydrogenase (G6PD) A- deficiency is prevalent in sub-Saharan Africa populations, and has been associated with protection from severe malaria. Whether females and/or males are protected by G6PD deficiency is uncertain, due in part to G6PD and malaria phenotypic complexity and misclassification. Almost all large association studies have genotyped a limited number of G6PD SNPs (e.g....

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Share to Chromosomes, Human, X
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25671784
DOI: 10.1371/journal.pgen.1004960
PMCID: PMC4335500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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