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Article

Allelic heterogeneity of G6PD deficiency in West Africa and severe malaria susceptibility.

European journal of human genetics : EJHG - 1 Aug 2009

Clark Taane G, Fry Andrew E, Auburn Sarah, Campino Susana, Diakite Mahamadou, Green Angela, Richardson Anna, Teo Yik Y, Small Kerrin, Wilson Jonathan, Jallow Muminatou, Sisay-Joof Fatou, Pinder Margaret, Sabeti Pardis, Kwiatkowski Dominic P, Rockett Kirk A

Abstract excerpt

Several lines of evidence link glucose-6-phosphate dehydrogenase (G6PD) deficiency to protection from severe malaria. Early reports suggested most G6PD deficiency in sub-Saharan Africa was because of the 202A/376G G6PD A- allele, and recent association studies of G6PD deficiency have employed genotyping as a convenient way to determine enzyme status. However, further work has suggested that other G6PD deficiency...

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Identifiers

PMID: 19223928
DOI: 10.1038/ejhg.2009.8
PMCID: PMC2986558

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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