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Article

Genetic determinants of glucose-6-phosphate dehydrogenase activity in Kenya.

BMC medical genetics - 9 Sept 2014

Shah Shivang S, Macharia Alex, Makale Johnstone, Uyoga Sophie, Kivinen Katja, Craik Rachel, Hubbart Christina, Wellems Thomas E, Rockett Kirk A, Kwiatkowski Dominic P, Williams Thomas N

Abstract excerpt

BACKGROUND: The relationship between glucose-6-phosphate dehydrogenase (G6PD) deficiency and clinical phenomena such as primaquine-sensitivity and protection from severe malaria remains poorly defined, with past association studies yielding inconsistent and conflicting results. One possibility is that examination of a single genetic variant might underestimate the presence of true effects in the presence of...

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PMID: 25201310
DOI: 10.1186/s12881-014-0093-6
PMCID: PMC4236593

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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