Article
Glucose-6-phosphate dehydrogenase deficiency and reduced haemoglobin levels in African children with severe malaria.
Malaria journal - 7 Jul 2016
Nguetse Christian N, Meyer Christian G, Adegnika Ayola Akim, Agbenyega Tsiri, Ogutu Bernhards R, Kremsner Peter G, Velavan Thirumalaisamy P
Abstract excerpt
BACKGROUND: Extensive studies investigating the role of host genetic factors during malaria associate glucose-6-phosphate dehydrogenase deficiency with relative protection. G6PD deficiency had been reported to associate with anti-malarial drug induced with haemolytic anaemia. METHODS: A total of 301 Gabonese, Ghanaian, and Kenyan children aged 6-120 months with severe malaria recruited in a multicentre trial on...
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