Article
Genotypic glucose-6-phosphate dehydrogenase (G6PD) deficiency protects against Plasmodium falciparum infection in individuals living in Ghana.
PloS one - 1 Jan 2021
Amoah Linda Eva, Asare Kwame Kumi, Dickson Donu, Abankwa Joana, Busayo Abena, Bredu Dorcas, Annan Sherifa, Asumah George Adu, Peprah Nana Yaw, Asamoah Alexander, Laurencia Malm Keziah
Abstract excerpt
INTRODUCTION: The global effort to eradicate malaria requires a drastic measure to terminate relapse from hypnozoites as well as transmission via gametocytes in malaria-endemic areas. Primaquine has been recommended for the treatment of P. falciparum gametocytes and P. vivax hypnozoites, however, its implementation is challenged by the high prevalence of G6PD deficient (G6PDd) genotypes in malaria endemic...
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