Article
Glucose-6-phosphate dehydrogenase polymorphisms and susceptibility to mild malaria in Dogon and Fulani, Mali.
Malaria journal - 11 Jul 2014
Maiga Bakary, Dolo Amagana, Campino Susana, Sepulveda Nuno, Corran Patrick, Rockett Kirk A, Troye-Blomberg Marita, Doumbo Ogobara K, Clark Taane G
Abstract excerpt
BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is associated with protection from severe malaria, and potentially uncomplicated malaria phenotypes. It has been documented that G6PD deficiency in sub-Saharan Africa is due to the 202A/376G G6PD A-allele, and association studies have used genotyping as a convenient technique for epidemiological studies. However, recent studies have shown...
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