Article
Interferon lambda-3 polymorphism and response to pegylated interferon in patients with hepatitis D.
Antiviral therapy - 1 Jan 2015
Abbas Zaigham, Yakoob Javed, Umer Muhammad A, Abbas Minaam, Hamid Saeed
Abstract excerpt
BACKGROUND: Specific single nucleotide polymorphisms (SNPs) near the interferon lambda-3 (IFNλ3) gene (formerly interleukin 28B) influence the response to treatment with interferon in hepatitis C patients. We aimed to investigate such an influence in hepatitis D patients. METHODS: The study population consisted of hepatitis D patients who were previously treated with pegylated interferon for one year and who were...
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