Effects of polymorphisms in interferon λ 3 (interleukin 28B) on sustained virologic response to therapy in patients with chronic hepatitis D virus infection.

doi:10.1016/j.cgh.2014.01.043

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Article

Effects of polymorphisms in interferon λ 3 (interleukin 28B) on sustained virologic response to therapy in patients with chronic hepatitis D virus infection.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Oct 2014

Yilmaz Emre, Baran Bulent, Soyer Ozlem Mutluay, Onel Mustafa, Onel Derya, Ormeci Asli Cifcibasi, Gokturk Suut, Evirgen Sami, Akyuz Filiz, Demir Kadir, Besisik Fatih, Kaymakoglu Sabahattin, Karaca Cetin

Abstract excerpt

BACKGROUND & AIMS: We investigated the association between interferon λ 3 (IFNL3) genotype (also known as interleukin 28B) and response to IFNα therapy in patients with chronic hepatitis D virus (HDV) infection. METHODS: We studied IFNL3 genotypes of 32 patients (19 men; median age, 42.5 y) with chronic HDV infection. Nineteen patients (59%) were treated with pegylated IFNα and 13 patients (41%) were treated with...

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PMID: 24582569
DOI: 10.1016/j.cgh.2014.01.043

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IFNL3

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