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Article

IL28B genetic variation and treatment response in patients with hepatitis C virus genotype 3 infection.

Hepatology (Baltimore, Md.) - 1 Mar 2011

Moghaddam Amir, Melum Espen, Reinton Nils, Ring-Larsen Helmer, Verbaan Hans, Bjøro Kristian, Dalgard Olav

Abstract excerpt

UNLABELLED: Polymorphisms near the IL28B gene, which code for interferon (IFN)-λ3, predict response to pegylated interferon-α (PEG-IFN) and ribavirin treatment in hepatitis C virus (HCV) genotype 1 infected patients. Follow-up studies of the effect of IL28B gene in HCV non-genotype 1 infected patients have almost always used predominantly HCV genotype 2-infected or mixed genotype 2/3-infected cohorts with results...

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PMID: 21374656
DOI: 10.1002/hep.24154

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