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Article

β-catenin alteration is rare in hepatocellular carcinoma with steatohepatitic features: immunohistochemical and mutational study.

Virchows Archiv : an international journal of pathology - 1 Nov 2015

Ando Sumiyo, Shibahara Junji, Hayashi Akimasa, Fukayama Masashi

Abstract excerpt

Hepatocellular carcinoma (HCC) with steatohepatitic features (steatohepatitic HCC, SH-HCC) is a histological subset of HCC, highly associated with metabolic disease and underlying steatohepatitis. Although it has distinct clinicopathologic characteristics, little is known about the immunophenotype or genetic characteristics of SH-HCC. We conducted an immunohistochemical analysis on a tissue microarray containing...

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beta Catenin
Carcinoma, Hepatocellular
Glutamate-Ammonia Ligase
Hedgehog Proteins
Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Liver Neoplasms

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Identifiers

PMID: 26311355
DOI: 10.1007/s00428-015-1836-2

Genes

CTNNB1
SALL4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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