Article
Association of TNF-alpha gene polymorphisms with systemic lupus erythematosus in Taiwanese patients.
Lupus - 1 Oct 2009
Lin Y-J, Chen R-H, Wan L, Sheu Jj-C, Huang C-M, Lin C-W, Chen S-Y, Lai C-H, Lan Y-C, Hsueh K-C, Tsai C-H, Lin T-H, Huang Y-M, Chao K, Chen D-Y, Tsai F-J
Abstract excerpt
Tumour necrosis factor-alpha (TNF-alpha), an important proinflammatory cytokine, exerts a variety of physiological and pathogenic effects that lead to tissue destruction. Studies on the association of TNF-alpha genetic polymorphisms with systemic lupus erythematosus (SLE) have yielded inconclusive results. We investigated the association of TNF-alpha genetic polymorphisms (-1031T/C, -863C/A, -857T/C, -308A/G and...
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