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Article

Impact of TNF-α and LTα gene polymorphisms on genetic susceptibility in Indian SLE patients.

Human immunology - 1 Feb 2017

Umare Vinod D, Pradhan Vandana D, Rajadhyaksha Anjali G, Patwardhan Manisha M, Ghosh Kanjaksha, Nadkarni Anita H

Abstract excerpt

The promoter polymorphisms of tumour necrosis factor-α (TNF-α) and intronic Lymphotoxin-α (LTα) have been implicated as genetic risk factors for systemic lupus erythematosus (SLE) in various ethnic groups. The aim of this study was to investigate an impact of TNF-α (-308G/A; 238G/A) and LTα (+252A/G) gene polymorphisms in disease susceptibility among Indian 200 SLE patients along with 201 healthy controls. The...

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Source

Identifiers

PMID: 27838362
DOI: 10.1016/j.humimm.2016.11.002

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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