Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polo-Like Kinase-1 Is a Pivotal Regulator of Microtubule Assembly During Mouse Oocyte Meiotic Maturation, Fertilization, and Early Embryonic Mitosis1

1 Aug 2002

Abstract excerpt

Polo-like kinases (Plks) are a family of serine/threonine protein kinases that have been activated through phosphorylation. The activity of these kinases has been shown to be required for regulating multiple stages of mitotic progression in somatic cells. In this experiment, the changes in Plk1 expression were detected in mouse oocytes through Western blotting. The subcellular localization of Plk1 during oocyte...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Microtubule and mitosis dynamics
Share to Pluripotent Stem Cells Research
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12135894
DOI: 10.1095/biolreprod67.2.546

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polo-Like Kinase-1 Is a Pivotal Regulator of Microtubule Assembly During Mouse Oocyte Meiotic Maturation, Fertilization, and Early Embryonic Mitosis1PMID 12135894Read ↗

Multiple Requirements of PLK1 during Mouse Oocyte MaturationSemantic proximity Read ↗

PAK4 Regulates Actin and Microtubule Dynamics during Meiotic Maturation in Mouse OocyteSemantic proximity Read ↗

Aurora-A Is a Critical Regulator of Microtubule Assembly and Nuclear Activity in Mouse Oocytes, Fertilized Eggs, and Early Embryos1Semantic proximity Read ↗

BRCA1 Is Required for Meiotic Spindle Assembly and Spindle Assembly Checkpoint Activation in Mouse Oocytes1Semantic proximity Read ↗

Polo-like kinase 1 is essential for the first mitotic division in the mouse embryoSemantic proximity Read ↗

Ste20‐like kinase activity promotes meiotic resumption and spindle microtubule stability in mouse oocytesSemantic proximity Read ↗

Echinoderm Microtubule Associated Protein Like 1 Is Indispensable for Oocyte Spindle Assembly and Meiotic Progression in MiceSemantic proximity Read ↗

Meiotic spindle formation in mammalian oocytes: implications for human infertility†Semantic proximity Read ↗

Kinesin KIF3A regulates meiotic progression and spindle assembly in oocyte meiosisSemantic proximity Read ↗

Centrosome dynamics during mammalian oocyte maturation with a focus on meiotic spindle formationSemantic proximity Read ↗

PLK1 is required for chromosome compaction and microtubule organization in mouse oocytesSemantic proximity Read ↗

JAK2 inhibitor CEP-33779 prevents mouse oocyte maturation in vitroSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.