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Article

Virus-induced target cell activation reconciles set-point viral load heritability and within-host evolution.

Epidemics - 1 Dec 2013

Hool Anna, Leventhal Gabriel E, Bonhoeffer Sebastian

Abstract excerpt

The asymptomatic phase of HIV-1 infections is characterised by a stable set-point viral load (SPVL) within patients. The SPVL is a strong predictor of disease progression and shows considerable variation of multiple orders of magnitude between patients. Recent studies have found that the SPVL in donor and recipient pairs is strongly correlated indicating that the virus genotype strongly influences viral load....

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PMID: 24267873
DOI: 10.1016/j.epidem.2013.09.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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