Article
Evx1 is a postmitotic determinant of v0 interneuron identity in the spinal cord.
Neuron - 1 Feb 2001
Moran-Rivard L, Kagawa T, Saueressig H, Gross M K, Burrill J, Goulding M
Abstract excerpt
Interneurons in the ventral spinal cord are essential for coordinated locomotion in vertebrates. During embryogenesis, the V0 and V1 classes of ventral interneurons are defined by expression of the homeodomain transcription factors Evx1/2 and En1, respectively. In this study, we show that Evx1 V0 interneurons are locally projecting intersegmental commissural neurons. In Evx1 mutant embryos, the majority of V0...
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