Article
SF3B1 mutation is a rare event in Chinese patients with acute and chronic myeloid leukemia.
Clinical biochemistry - 1 May 2013
Yang Jing, Qian Jun, Yao Dong-ming, Qian Si-xuan, Qian Wei, Lin Jiang, Xiao Gao-fei, Wang Cui-zhu, Deng Zhao-qun, Ma Ji-chun, Chen Xing-xing
Abstract excerpt
OBJECTIVE: Somatic mutations of SF3B1 gene have recently been identified in myelodysplastic syndrome and chronic lymphocytic leukemia. The frequency and clinical relevance of SF3B1 mutations have been rarely studied in acute myeloid leukemia (AML) and chronic myeloid leukemia (CML). The present study was aimed to analyze the frequency of SF3B1 mutations in AML and CML. DESIGNS AND METHODS: High-resolution melting...
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