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Article

A novel NOTCH3 mutation identified in patients with oral cancer by whole exome sequencing.

International journal of molecular medicine - 1 Jun 2017

Yi Yanjun, Tian Zhuowei, Ju Houyu, Ren Guoxin, Hu Jingzhou

Abstract excerpt

Oral cancer is a serious disease caused by environmental factors and/or susceptible genes. In the present study, in order to identify useful genetic biomarkers for cancer prediction and prevention, and for personalized treatment, we detected somatic mutations in 5 pairs of oral cancer tissues and blood samples using whole exome sequencing (WES). Finally, we confirmed a novel nonsense single-nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28440410
DOI: 10.3892/ijmm.2017.2965

Genes

NOTCH3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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