Article
Developmental regulation of neural map formation in the mouse olfactory system.
Developmental neurobiology - 1 Jun 2015
Nishizumi Hirofumi, Sakano Hitoshi
Abstract excerpt
In the mouse olfactory system, various odorants are detected by approximately 1000 different odorant receptors (ORs) expressed in the olfactory sensory neurons (OSNs). It is well established that each OSN expresses only one functional OR gene in a monoallelic manner. Furthermore, OSN axons expressing the same OR converge to a set of glomeruli in the olfactory bulb (OB). During embryonic development, a coarse map...
Topics
- Animals
- Axons
- Brain Mapping
- Mice
- Mutation
- Olfactory Pathways
- Olfactory Receptor Neurons
- Receptors, G-Protein-Coupled
- Receptors, Odorant
- Signal Transduction
